Paper published in npj Systems Biology and Applications (CML treatment response)

The paper “Early dynamics of chronic myeloid leukemia on nilotinib predicts deep molecular response” was published in npj Systems Biology and Applications 8, 39 (2022). doi:10.1038/s41540-022-00248-3

Patients with different responses to nilotinib could be classified by parameters of a simple dynamical model estimated from two routinely measured laboratory values. Data from only three initial time points identified, with high accuracy, patients who failed to reach the treatment goal.

The work is also described on the Research page.

The University of Tokyo, Tokyo Medical and Dental University (now Institute of Science Tokyo), and the University of Fukui issued a joint press release on this work (13 October 2022).

• Press release (in Japanese) (Tokyo Medical and Dental University, 13 October 2022)
• Press release (in Japanese) (International Research Center for Neurointelligence, the University of Tokyo, 14 October 2022)
• Press materials (PDF, in Japanese)