Press releases on Bioprocess Engineering Lab · Kajita Group

Paper published in Physical Review Research (mitochondrial alignment)

Mon, 29 Apr 2024 00:00:00 +0000

The paper “Active thermodynamic force driven mitochondrial alignment” was published as a Letter in Physical Review Research 6, L022024 (2024). doi:10.1103/PhysRevResearch.6.L022024

We showed theoretically that ATP production and ATP-dependent non-directional movement of mitochondria are sufficient for their nearly regular alignment, even without an explicit repulsive force between them or any internal states or memory of the mitochondria.

Paper published in npj Systems Biology and Applications (CML treatment response)

Thu, 13 Oct 2022 00:00:00 +0000

The paper “Early dynamics of chronic myeloid leukemia on nilotinib predicts deep molecular response” was published in npj Systems Biology and Applications 8, 39 (2022). doi:10.1038/s41540-022-00248-3

Patients with different responses to nilotinib could be classified by parameters of a simple dynamical model estimated from two routinely measured laboratory values. Data from only three initial time points identified, with high accuracy, patients who failed to reach the treatment goal.